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Metabolic Disorder

What are metabolic disorders?

A metabolic disorder occurs when the metabolic process fails and causes the body to have too much or too little of the essential substances needed to stay healthy. Our bodies are quite sensitive to errors in metabolism. The body must have amino acids and many types of proteins to perform all of its functions. For example, the brain needs calcium, potassium, and sodium to generate electrical impulses, and lipids (fats and oils) to maintain a healthy nervous system. 

Metabolic disorders can take many forms, these include:

  • A missing enzyme or vitamin that’s necessary for essential chemical reactions within the body.
  • Abnormal chemical reactions; that may hinder the metabolic process.
  • Disease in the liver, pancreas, endocrine glands, or other organs involved in metabolism.
  • Nutritional deficiencies.

Hyperlipidemia is an umbrella term that refers to any of the several acquired or genetic disorders that result in a high level of lipids (fats, cholesterol and triglycerides) circulating in the blood. These lipids can enter the walls of arteries and increase your risk of developing atherosclerosis (hardening of the arteries), that may result in stroke, heart attack or the need to amputate. The risk of atherosclerosis is higher amongst smokers, diabetics, high blood pressure & kidney patients.

Stem Cells

 

Stem cells hold the potential for growing into other tissues such as bone, cartilage and muscle, making them suitable for treating metabolic disorders such as diabetes, insulin resistance and high levels of blood lipids.

Stem-cell-based formulations significantly lowered glucose and serum triglyceride levels in the mice. Besides, the formulations significantly reduced serum insulin levels. Of all the formulations, stem cell suspension remarkably reduced inflammation and triglycerides in the liver.

The cell suspension also dramatically increased protein content in the skeletal muscle and enhanced the expression of the GLUT4 gene, which encodes GLUT4 protein. This protein transports glucose and makes the muscle tissue sensitive to insulin.